Running back handcuffs have fallen out of favor in recent years with the growth of committees and depth at the position. Pure handcuffs, players without standalone value, are a good way to tie up an important roster spot for much of the season, only to see that player not match the starter’s value when you plug him in for a key late-season tilt. Even on my extreme Zero RB teams, I tend to eschew handcuffs for players with better profiles and more upside.